USA 6-Day San Francisco Ultimate Guide | Napa & Sonoma Wine Tour, Vineyards, Tastings & Beautiful Wine Country

VERDICT: We gave 4 out of 5 tickets and here’s why!

This guide forms part of our complete USA Travel Guide, featuring scenic road trips, iconic destinations, practical travel advice and honest first-hand travel experiences from across the United States.

This article is part of our 6-Day San Francisco Road Trip: Ultimate Guide. series. Over six days, we explored San Francisco’s unmistakable landmarks, waterfront attractions and fascinating neighbourhoods before taking day trips to Alcatraz, Muir Woods, Napa Valley and Carmel-by-the-Sea. From crossing the Golden Gate Bridge and exploring Pier 39 to walking through ancient redwoods and discovering California wine country, this series brings together our complete itinerary, personal experiences and practical visitor advice. Read the complete six-day guide here.


Two famous wine regions, family-run vineyards and one unforgettable guided day trip

On our San Francisco/San Diego trip we decided we couldn’t come so close to Napa Valley & Sonoma & not do a wine tour… we’re hardly connoisseurs but do enjoy a nice glass of wine.

We prearranged a trip with Green Dream Tours & our tour guide was Chris. He was fantastic! Funny, knowledgeable & an excellent driver in the crazy San Francisco traffic.

We learned a lot through him like: What was the Otis Redding song that was inspired by renting a houseboat in Sausalito, California? ‘Sittin on the Dock of the Bay’!

San Francisco is known for being the birthplace of mountain biking… huh, who knew?! Interestingly, the Agricultural Reserve has designated any land that is already farmland be sold or operated on only as farmland & cannot be redeveloped or subdivided.

We stopped to get pictures of the most used building in San Francisco for wedding photos, the Palace of Fine Arts. We then passed through the Robin Williams Tunnel (coincidentally it was the 3rd anniversary of his death the same day).

Sonoma has been known as a place with hoity toity wineries but that is so not true. The majority of the vineyards have been family run for many years.

We visited 2 –
Cline Cellars which was beautifully run by the Cline Family. There are wine tastings, a gift shop, exotic birds, gorgeous grounds & of course the vineyards themselves to see.

Our host was named Mark, an architect by day, who was quite charming & knowledgeable about the wines he was serving & also about the family’s vineyard that has been around since 1989.

Founded in 1982 by Fred and Nancy Cline in Oakley, California, Cline Family Cellars began with wines crafted from historic Mourvèdre, Zinfandel, and Carignane vines, some planted as early as the 1880s. In 1989, the family moved the winery to a 350-acre former horse farm in Sonoma-Carneros, where they raised their seven children and expanded their vineyards throughout Sonoma County.

A pioneer among the original Rhône Rangers, Fred helped introduce California wine lovers to Syrah, Viognier, Marsanne, and Roussanne while continuing to champion Sonoma classics like Pinot Noir and Chardonnay.

We then travelled down the road a ways to Homewood Winery. This was a much smaller vineyard, run by one man who just… loves… wine. Mostly red wine, but he does create some whites as well.

Dave Homewood started as a home winemaker in 1983 when he and two friends produced wine from a ton of Alexander Valley cabernet sauvignon. The following year they added a ton of Alexander Valley chardonnay. In 1986, they purchased their first ton of chardonnay from the newly formed Carneros AVA (appellation) and the styles of wine that Homewood Winery became noted for were born.

Our host this time was Robert. The wine tasting was done with suggestions of food pairings so was pretty cool as well. We did purchase a 2014 Roussanne to take home with us WHICH I absentmindedly packed in our CARRY ON… I saw the perfect spot where it wouldn’t get broken, popped it in there… and of course, we had to give it up at security…

It was really interesting to see the love these people have for their craft & their properties. We found the enterprising way they added more things to their vineyards (tasting rooms, gift shops, etc) was charming & still kept the family run feel.

This was an amazing trip and we absolutely enjoyed ourselves, not only in the wine tasting rooms but also learning about vineyards and optimizing grape growth.


What is the prettiest winery in Sonoma?

While “prettiest” is a matter of taste, Ferrari-Carano Vineyards and Winery in Dry Creek Valley is widely considered a top contender with its stunning Italian-style villa, sweeping vineyard backdrops, and world-class gardens featuring thousands of tulips and roses. 

What was the name of the first winery in Sonoma, California that is still operating today?

The first commercial winery in Sonoma, California that is still operating today is the Buena Vista Winery, which was founded in 1857 by Count Agoston Haraszthy.


Green Dream Tours: Visitor Information

Green Dream Tours continues to offer a full-day Napa and Sonoma experience from San Francisco. Its current Ultimate Napa & Sonoma Wine Tour is approximately nine hours, departs from Fisherman’s Wharf and includes tastings. Adult prices currently begin at $179 US, but the wineries visited can change. Use this updated link: Find a similar Napa and Sonoma wine tour with Green Dream Tours


Best Route From San Francisco to Napa Valley

Recommended scenic route: Golden Gate Bridge

Distance: Approximately 80–90 kilometres/50–55 miles
Driving time: Approximately 1¼ to 1½ hours without heavy traffic
Weekend travel time: As much as two hours

  1. Leave central San Francisco and follow signs for US-101 North.
  2. Cross the Golden Gate Bridge.
  3. Continue north through Marin County on US-101.
  4. Take the exit for CA-37 East toward Napa and Vallejo.
  5. Continue on CA-37 East.
  6. Turn onto CA-121 North toward Napa.
  7. Continue onto CA-29 North for Downtown Napa, Yountville, St. Helena and Calistoga.

This route provides the best overall experience because it includes the Golden Gate Bridge and takes you through Marin County toward wine country.

Fastest alternative: Bay Bridge

From downtown San Francisco, take I-80 East across the Bay Bridge, remain on I-80 toward Vallejo, and then follow CA-29 North into Napa.

The Bay Bridge route may be quicker depending on where you are staying and the time of day. Visit Napa Valley estimates approximately one hour from San Francisco during quieter weekday periods and as much as two hours on busy weekends. Visit Napa Valley

Important driving advice

If you intend to taste wine, a guided tour is unquestionably the better option. California’s driving limits still apply in wine country, regardless of how charming the tasting room was or how generously the host poured.


Top Five Things to Do Near Napa Valley

1. Explore Downtown Napa and Oxbow Public Market

Walk along the Napa Riverfront before visiting Oxbow Public Market for coffee, local food, artisan products, cheese and, naturally, more wine. Its collection of independent vendors makes it a good lunch stop before or after a winery visit. Visit Napa Valley

2. Ride the Napa Valley Wine Train

The Napa Valley Wine Train combines dining and sightseeing aboard restored railway carriages. Different experiences travel through the valley, with selected packages incorporating winery visits. Book well ahead during weekends and the autumn harvest season.

3. Visit Yountville

Yountville is known for landscaped streets, tasting rooms, galleries and an exceptional restaurant scene. It is compact enough to explore on foot and provides a polished but relaxed break between vineyard appointments.

4. Explore Sonoma Plaza and Sonoma State Historic Park

Sonoma Plaza is surrounded by shops, restaurants, tasting rooms and historic buildings. Nearby Sonoma State Historic Park incorporates Mission San Francisco Solano, Sonoma Barracks and other important sites connected to early California history. California State Parks

5. Visit Castello di Amorosa and Calistoga

Continue north through Napa Valley to Calistoga, known for hot springs, wineries and a relaxed small-town atmosphere. Nearby Castello di Amorosa is an elaborate Tuscan-style winery resembling a medieval castle. Reservations are strongly recommended for winery tastings throughout Napa Valley.


Planning Your Trip?

Before you go, don’t forget to book the essentials:


With every trip, we offer feedback to travel companies along with honest views for you, the reader. We rate adventures on a scale of one to five tickets, judged on quality, service, memorability, and price. A perfect ‘Ticket Rating’ of a five-ticket score means the experience was flawless and we’d eagerly return. Your desire to go back is the ultimate measure of a trip’s worth. Exclusive to My Return Ticket.



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